Positive Selection of Cd4(+) T Cells Is Induced in Vivo by Agonist and Inhibited by Antagonist Peptides

The nature of peptides that positively select T cells in the thymus remains poorly defined. Here we report an in vivo model to study the mechanisms of positive selection of CD4(+) T cells. We have restored positive selection of TCR transgenic CD4(+) thymocytes, arrested at the CD4(+)CD8(+) stage, du...

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Detalles Bibliográficos
Autores principales: Kraj, Piotr, Pacholczyk, Rafal, Ignatowicz, Hanna, Kisielow, Pawel, Jensen, Peter, Ignatowicz, Leszek
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193504/
https://www.ncbi.nlm.nih.gov/pubmed/11514598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193504/
https://www.ncbi.nlm.nih.gov/pubmed/11514598

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