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Arrested B Lymphopoiesis and Persistence of Activated B Cells in Adult Interleukin 7(−/)− Mice

Interleukin 7 is a crucial factor for the development of murine T and B lymphocytes. We now report that, in the absence of interleukin 7, B lymphocyte production takes place exclusively during fetal and perinatal life, ceasing after 7 wk of age. In peripheral organs, however, the pool of B lymphocyt...

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Detalles Bibliográficos
Autores principales: Carvalho, Thiago L., Mota-Santos, Tomaz, Cumano, Ana, Demengeot, Jocelyne, Vieira, Paulo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193519/
https://www.ncbi.nlm.nih.gov/pubmed/11602642