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Splenic T Zone Development Is B Cell Dependent

The factors regulating growth and patterning of the spleen are poorly defined. We demonstrate here that spleens from B cell–deficient mice have 10-fold reduced expression of the T zone chemokine, CCL21, a threefold reduction in T cell and dendritic cell (DC) numbers, and reduced expression of the T...

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Detalles Bibliográficos
Autores principales: Ngo, Vu N., Cornall, Richard J., Cyster, Jason G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193532/
https://www.ncbi.nlm.nih.gov/pubmed/11733579