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Treatment with Soluble Interleukin-15Rα Exacerbates Intracellular Parasitic Infection by Blocking the Development of Memory CD8(+) T Cell Response

Interferon (IFN)-γ–producing CD8(+) T cells are important for the successful resolution of the obligate intracellular parasite Toxoplasma gondii by preventing the reactivation or controlling a repeat infection. Previous reports from our laboratory have shown that exogenous interleukin (IL)-15 treatm...

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Detalles Bibliográficos
Autores principales: Khan, Imtiaz A., Moretto, Magali, Wei, Xiao-qing, Williams, Martha, Schwartzman, Joseph D., Liew, Foo Y.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193543/
https://www.ncbi.nlm.nih.gov/pubmed/12045244
http://dx.doi.org/10.1084/jem.20011915