Targeted Disruption of LIGHT Causes Defects in Costimulatory T Cell Activation and Reveals Cooperation with Lymphotoxin β in Mesenteric Lymph Node Genesis

The recently described tumor necrosis factor (TNF) family member LIGHT (herpes virus entry mediator [HVEM]-L/TNFSF14), a ligand for the lymphotoxin (LT)β receptor, HVEM, and DcR3, was inactivated in the mouse. In contrast to mice deficient in any other member of the LT core family, LIGHT(−/−) mice d...

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Detalles Bibliográficos
Autores principales: Scheu, Stefanie, Alferink, Judith, Pötzel, Tobias, Barchet, Winfried, Kalinke, Ulrich, Pfeffer, Klaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193565/
https://www.ncbi.nlm.nih.gov/pubmed/12070288
http://dx.doi.org/10.1084/jem.20020215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193565/
https://www.ncbi.nlm.nih.gov/pubmed/12070288
http://dx.doi.org/10.1084/jem.20020215

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