Aging Leads to Disturbed Homeostasis of Memory Phenotype CD8(+) Cells

Examining the rate of in vivo T cell turnover (proliferation) in aged mice revealed a marked reduction in turnover at the level of memory-phenotype CD44(hi) CD8(+) cells relative to young mice. Based on adoptive transfer experiments, the reduced turnover of aged CD44(hi) CD8(+) cells reflected an in...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaohong, Fujii, Hideki, Kishimoto, Hidehiro, LeRoy, Eric, Surh, Charles D., Sprent, Jonathan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193587/
https://www.ncbi.nlm.nih.gov/pubmed/11828003
http://dx.doi.org/10.1084/jem.20011267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193587/
https://www.ncbi.nlm.nih.gov/pubmed/11828003
http://dx.doi.org/10.1084/jem.20011267

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