Cargando…

Aging Leads to Disturbed Homeostasis of Memory Phenotype CD8(+) Cells

Examining the rate of in vivo T cell turnover (proliferation) in aged mice revealed a marked reduction in turnover at the level of memory-phenotype CD44(hi) CD8(+) cells relative to young mice. Based on adoptive transfer experiments, the reduced turnover of aged CD44(hi) CD8(+) cells reflected an in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiaohong, Fujii, Hideki, Kishimoto, Hidehiro, LeRoy, Eric, Surh, Charles D., Sprent, Jonathan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193587/ https://www.ncbi.nlm.nih.gov/pubmed/11828003 http://dx.doi.org/10.1084/jem.20011267

Ejemplares similares

Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8(+) T Cells
por: Judge, Adam D., et al.
Publicado: (2002)

Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8(+) Cells but Are Not Required for Memory Phenotype CD4(+) Cells
por: Tan, Joyce T., et al.
Publicado: (2002)

Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8(+) T Cells
por: Kieper, William C., et al.
Publicado: (2002)

A major histocompatibility complex class I–dependent subset of memory phenotype CD8(+) cells
por: Boyman, Onur, et al.
Publicado: (2006)

A Role for Fas in Negative Selection of Thymocytes In Vivo
por: Kishimoto, Hidehiro, et al.
Publicado: (1998)

Requirements for Peptide-induced T Cell Receptor Downregulation on Naive CD8(+) T Cells
por: Cai, Zeling, et al.
Publicado: (1997)

Antiviral CD4(+) memory T cells are IL-15 dependent
por: Purton, Jared F., et al.
Publicado: (2007)

CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells
por: Cho, Jae-Ho, et al.
Publicado: (2016)

T Cells Can Use Either T Cell Receptor or Cd28 Receptors to Absorb and Internalize Cell Surface Molecules Derived from Antigen-Presenting Cells
por: Hwang, Inkyu, et al.
Publicado: (2000)

Negative Selection in the Thymus Includes Semimature T Cells
por: Kishimoto, Hidehiro, et al.
Publicado: (1997)

Several Different Cell Surface Molecules Control Negative Selection of Medullary Thymocytes
por: Kishimoto, Hidehiro, et al.
Publicado: (1999)

MAGT1-mediated disturbance of Mg(2+) homeostasis lead to exhausted of HBV-infected NK and CD8(+) T cells
por: Diao, Bo, et al.
Publicado: (2017)

Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells
por: Jensen, Isaac J, et al.
Publicado: (2021)

DNA as an Adjuvant: Capacity of Insect DNA and Synthetic Oligodeoxynucleotides to Augment T Cell Responses to Specific Antigen
por: Sun, Siquan, et al.
Publicado: (1998)

An intense form of homeostatic proliferation of naive CD8(+) cells driven by IL-2
por: Cho, Jae-Ho, et al.
Publicado: (2007)

TRAF3 Regulates Homeostasis of CD8(+) Central Memory T Cells
por: Yi, Zuoan, et al.
Publicado: (2014)

Homeostatic T Cell Proliferation: How Far Can T Cells Be Activated to Self-Ligands?
por: Surh, Charles D., et al.
Publicado: (2000)

Spontaneous Proliferation of CD4(+) T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8(+) T Cells
por: Kim, Juhee, et al.
Publicado: (2018)

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
por: Kolumam, Ganesh A., et al.
Publicado: (2005)

Phenotypic and Immunometabolic Aspects on Stem Cell Memory and Resident Memory CD8(+) T Cells
por: La Manna, Marco Pio, et al.
Publicado: (2022)

Phenotypic and Functional Separation of Memory and Effector Human CD8(+) T Cells
por: Hamann, Dörte, et al.
Publicado: (1997)

Tissue-Resident Memory CD8(+) T Cells: From Phenotype to Function
por: Topham, David J., et al.
Publicado: (2018)

Lineage relationships, homeostasis, and recall capacities of central– and effector–memory CD8 T cells in vivo
por: Bouneaud, Cécile, et al.
Publicado: (2005)

Epigenetic Maintenance of Acquired Gene Expression Programs during Memory CD8 T Cell Homeostasis
por: Abdelsamed, Hossam A., et al.
Publicado: (2018)

Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis
por: Abdelsamed, Hossam A., et al.
Publicado: (2017)

IL-21 in Homeostasis of Resident Memory and Exhausted CD8 T Cells during Persistent Infection
por: Ren, Heather M., et al.
Publicado: (2020)

Activation phenotype, rather than central– or effector–memory phenotype, predicts the recall efficacy of memory CD8(+) T cells
por: Hikono, Hirokazu, et al.
Publicado: (2007)

Consequences of Disturbing Manganese Homeostasis
por: Baj, Jacek, et al.
Publicado: (2023)

Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells
por: Berton, Roger R., et al.
Publicado: (2023)

Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8(+) T cells
por: Thiele, Daniel, et al.
Publicado: (2020)

Secondary memory CD8(+) T cells are more protective but slower to acquire a central–memory phenotype
por: Jabbari, Ali, et al.
Publicado: (2006)

CD70–CD27 ligation between neural stem cells and CD4(+) T cells induces Fas–FasL-mediated T-cell death
por: Lee, Eun Mi, et al.
Publicado: (2013)

Redefining the Foreign Antigen and Self-Driven Memory CD4(+) T-Cell Compartments via Transcriptomic, Phenotypic, and Functional Analyses
por: Kawabe, Takeshi, et al.
Publicado: (2022)

CD8(+)CD122(+) T-Cells: A Newly Emerging Regulator with Central Memory Cell Phenotypes
por: Liu, Junfeng, et al.
Publicado: (2015)

CD40 ligand stimulation affects the number and memory phenotypes of human peripheral CD8(+) T cells
por: Choi, Haeyoun, et al.
Publicado: (2023)

Comparative Effects of Deferiprone and Salinomycin on Lead-Induced Disturbance in the Homeostasis of Intrarenal Essential Elements in Mice
por: Gluhcheva, Yordanka, et al.
Publicado: (2022)

Multiple Choices: Regulation of Memory CD8 T Cell Generation and Homeostasis by Interleukin (IL)-7 and IL-15
por: Prlic, Martin, et al.
Publicado: (2002)

Eomes identifies thymic precursors of self-specific memory-phenotype CD8(+) T cells
por: Miller, Christine H., et al.
Publicado: (2020)

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy
por: Sckisel, Gail D., et al.
Publicado: (2017)

Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype
por: Forget, Marie-Andrée, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pfjtvredph1kq3f291a88ft6jf