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+1 Frameshifting as a Novel Mechanism to Generate a Cryptic Cytotoxic T Lymphocyte Epitope Derived from Human Interleukin 10

Recent data indicate that some cytotoxic T cells (CTLs) recognize so-called cryptic epitopes, encoded by nonprimary open reading frame (ORF) sequences or other nonclassical expression pathways. We describe here a novel mechanism leading to generation of a cryptic CTL epitope. We isolated from the sy...

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Detalles Bibliográficos
Autores principales: Saulquin, Xavier, Scotet, Emmanuel, Trautmann, Lydie, Peyrat, Marie-Alix, Halary, Franck, Bonneville, Marc, Houssaint, Elisabeth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193594/
https://www.ncbi.nlm.nih.gov/pubmed/11828010
http://dx.doi.org/10.1084/jem.20011399