Cargando…

+1 Frameshifting as a Novel Mechanism to Generate a Cryptic Cytotoxic T Lymphocyte Epitope Derived from Human Interleukin 10

Recent data indicate that some cytotoxic T cells (CTLs) recognize so-called cryptic epitopes, encoded by nonprimary open reading frame (ORF) sequences or other nonclassical expression pathways. We describe here a novel mechanism leading to generation of a cryptic CTL epitope. We isolated from the sy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saulquin, Xavier, Scotet, Emmanuel, Trautmann, Lydie, Peyrat, Marie-Alix, Halary, Franck, Bonneville, Marc, Houssaint, Elisabeth
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193594/ https://www.ncbi.nlm.nih.gov/pubmed/11828010 http://dx.doi.org/10.1084/jem.20011399

Ejemplares similares

AIDS virus–specific CD8(+) T lymphocytes against an immunodominant cryptic epitope select for viral escape
por: Maness, Nicholas J., et al.
Publicado: (2007)

Glycan-regulated Antigen Processing of a Protein in the Endoplasmic Reticulum Can Uncover Cryptic Cytotoxic T Cell Epitopes
por: Wood, Philip, et al.
Publicado: (1998)

Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes
por: Tan, Linda C, et al.
Publicado: (2000)

Murine Cytotoxic T Lymphocytes Recognize an Epitope in an EBNA-1 Fragment, but Fail to Lyse EBNA-1–expressing Mouse Cells
por: Mukherjee, Siddhartha, et al.
Publicado: (1998)

Crystal Structure of the Human Natural Killer Cell Activating Receptor KIR2DS2 (CD158j)
por: Saulquin, Xavier, et al.
Publicado: (2003)

CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription
por: Bansal, Anju, et al.
Publicado: (2010)

CYTOTOXIC THYMUS-DERIVED LYMPHOCYTES IN CEREBROSPINAL FLUID OF MICE WITH LYMPHOCYTIC CHORIOMENINGITIS
por: Zinkernagel, R. M., et al.
Publicado: (1973)

ROLE OF H-2 LYMPHOCYTE-DEFINED AND SEROLOGICALLY-DEFINED COMPONENTS IN THE GENERATION OF CYTOTOXIC LYMPHOCYTES
por: Alter, Barbara J., et al.
Publicado: (1974)

Role of CD8 in Aberrant Function of Cytotoxic T Lymphocytes
por: Kessler, Benedikt, et al.
Publicado: (1997)

Physiological expression and function of the MDR1 transporter in cytotoxic T lymphocytes
por: Chen, Mei Lan, et al.
Publicado: (2020)

THE RELATIONSHIP OF CELL DIVISION TO THE GENERATION OF CYTOTOXIC ACTIVITY IN MIXED LYMPHOCYTE CULTURE
por: Cantor, Harvey, et al.
Publicado: (1974)

Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand
por: Suzuki, Ivy, et al.
Publicado: (1998)

High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo
por: Ogg, Graham S., et al.
Publicado: (1998)

IDIOTYPIC DETERMINANTS OF IMMUNOGLOBULIN M DETECTED ON THE SURFACE OF HUMAN LYMPHOCYTES BY CYTOTOXICITY ASSAYS
por: Wernet, P., et al.
Publicado: (1972)

Induction of an Antigen-specific, CD1-restricted Cytotoxic T Lymphocyte Response In vivo
por: Lee, Delphine J., et al.
Publicado: (1998)

Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis
por: Shaw, Michael K., et al.
Publicado: (1997)

DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors
por: Gilfillan, Susan, et al.
Publicado: (2008)

Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Regulates the Unfolding of Autoimmune Diabetes
por: Lühder, Fred, et al.
Publicado: (1998)

Melanoma Cells Present a MAGE-3 Epitope to CD4(+) Cytotoxic T Cells in Association with Histocompatibility Leukocyte Antigen DR11
por: Manici, Simona, et al.
Publicado: (1999)

Negative Regulation of T Cell Receptor–Lipid Raft Interaction by Cytotoxic T Lymphocyte–associated Antigen 4
por: Chikuma, Shunsuke, et al.
Publicado: (2003)

SYNERGISTIC OR ANTAGONISTIC EFFECT OF DIFFERENT ANTIBODY CONCENTRATIONS ON IN VITRO LYMPHOCYTE CYTOTOXICITY IN THE MOLONEY SARCOMA VIRUS SYSTEM
por: Skurzak, Henryk M., et al.
Publicado: (1972)

B7-1 Engagement of Cytotoxic T Lymphocyte Antigen 4 Inhibits T Cell Activation in the Absence of CD28
por: Fallarino, Francesca, et al.
Publicado: (1998)

Cytotoxic T Lymphocyte Antigen 4 and CD28 Modulate Cell Surface Raft Expression in Their Regulation of T Cell Function
por: Martin, Margarita, et al.
Publicado: (2001)

Induction of M3-Restricted Cytotoxic T Lymphocyte Responses by N-Formylated Peptides Derived from Mycobacterium tuberculosis
por: Chun, Taehoon, et al.
Publicado: (2001)

Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Can Regulate Dendritic Cell–induced Activation and Cytotoxicity of CD8(+) T Cells Independently of CD4(+)T Cell Help
por: McCoy, Kathy D., et al.
Publicado: (1999)

Costimulation by B7 Modulates Specificity of Cytotoxic T Lymphocytes: A Missing Link That Explains Some Bystander T Cell Activation
por: Zheng, Pan, et al.
Publicado: (1997)

Different Interleukin-1β Converting Enzyme (ICE) Family Protease Requirements for the Apoptotic Death of T Lymphocytes Triggered by Diverse Stimuli
por: Sarin, Apurva, et al.
Publicado: (1996)

Immature Dendritic Cells Acquire Cd8(+)Cytotoxic T Lymphocyte Priming Capacity upon Activation by T Helper Cell–Independent or–Dependent Stimuli
por: Schuurhuis, Danita H., et al.
Publicado: (2000)

Immunologic Self-Tolerance Maintained by Cd25(+)Cd4(+)Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
por: Takahashi, Takeshi, et al.
Publicado: (2000)

Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25(+)Cd4(+) Regulatory Cells That Control Intestinal Inflammation
por: Read, Simon, et al.
Publicado: (2000)

B7-1 or B7-2 Is Required to Produce the Lymphoproliferative Phenotype in Mice Lacking Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4)
por: Mandelbrot, Didier A., et al.
Publicado: (1999)

Cd8 Expression up to the Double-Positive CD3(Low/Intermediate) Stage of Thymic Differentiation Is Sufficient for Development of Peripheral Functional Cytotoxic T Lymphocytes
por: Zhang, X.-L., et al.
Publicado: (2001)

In Vivo Cytotoxic T Lymphocyte Elicitation by Mycobacterial Heat Shock Protein 70 Fusion Proteins Maps to a Discrete Domain and Is Cd4(+) T Cell Independent
por: Huang, Qian, et al.
Publicado: (2000)

Evidence for the Chronic in Vivo Production of Human T Cell Leukemia Virus Type I Rof and Tof Proteins from Cytotoxic T Lymphocytes Directed against Viral Peptides
por: Pique, Claudine, et al.
Publicado: (2000)

Rapid Cytotoxic T Lymphocyte Activation Occurs in the Draining Lymph Nodes After Cutaneous Herpes Simplex Virus Infection as a Result of Early Antigen Presentation and Not the Presence of Virus
por: Mueller, Scott N., et al.
Publicado: (2002)

The insulin A-chain epitope recognized by human T cells is posttranslationally modified
por: Mannering, Stuart I., et al.
Publicado: (2005)

Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms
por: Raposo, Bruno, et al.
Publicado: (2014)

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1β maturation by caspase-8
por: Maelfait, Jonathan, et al.
Publicado: (2008)

Cytotoxic T Lymphocyte Antigen 4 (CTLA4) Blockade Accelerates the Acute Rejection of Cardiac Allografts in CD28-deficient Mice: CTLA4 Can Function Independently of CD28
por: Lin, Hua, et al.
Publicado: (1998)

PEROXIDASE-MEDIATED MAMMALIAN CELL CYTOTOXICITY
por: Edelson, Paul J., et al.
Publicado: (1973)

Cannot write session to /tmp/vufind_sessions/sess_jc2oalopoqauvtupn6fcggr5eb