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Complement C3 Activation Is Required for Antiphospholipid Antibody-induced Fetal Loss

The antiphospholipid syndrome (APS) is characterized by recurrent fetal loss, vascular thrombosis, and thrombocytopenia occurring in the presence of antiphospholipid (aPL) antibodies. The pathogenesis of fetal loss and tissue injury in APS is incompletely understood, but is thought to involve platel...

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Detalles Bibliográficos
Autores principales: Holers, V. Michael, Girardi, Guillermina, Mo, Lian, Guthridge, Joel M., Molina, Hector, Pierangeli, Silvia S., Espinola, Ricardo, Xiaowei, Liu E., Mao, Dailing, Vialpando, Christopher G., Salmon, Jane E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193604/
https://www.ncbi.nlm.nih.gov/pubmed/11805148
http://dx.doi.org/10.1084/jem.200116116