Vav3 Modulates B Cell Receptor Responses by Regulating Phosphoinositide 3-Kinase Activation

To elucidate the mechanism(s) by which Vav3, a new member of the Vav family proteins, participates in B cell antigen receptor (BCR) signaling, we have generated a B cell line deficient in Vav3. Here we report that Vav3 influences phosphoinositide 3-kinase (PI3K) function through Rac1 in that phospha...

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Detalles Bibliográficos
Autores principales: Inabe, Kazunori, Ishiai, Masamichi, Scharenberg, Andrew M., Freshney, Norman, Downward, Julian, Kurosaki, Tomohiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193613/
https://www.ncbi.nlm.nih.gov/pubmed/11805146
http://dx.doi.org/10.1084/jem.20011571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193613/
https://www.ncbi.nlm.nih.gov/pubmed/11805146
http://dx.doi.org/10.1084/jem.20011571

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