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A Human Immunoglobulin λ Locus Is Similarly Well Expressed in Mice and Humans

Transgenic mice carrying a 380-kb region of the human immunoglobulin (Ig) λ light (L) chain locus in germline configuration were created. The introduced translocus on a yeast artificial chromosome (YAC) accommodates the most proximal Igλ variable region (V) gene cluster, including 15 Vλ genes that c...

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Detalles Bibliográficos
Autores principales:	Popov, Andrei V., Zou, Xiangang, Xian, Jian, Nicholson, Ian C., Brüggemann, Marianne
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193639/ https://www.ncbi.nlm.nih.gov/pubmed/10330440

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