A Kinetic Threshold between Negative and Positive Selection Based on the Longevity of the T Cell Receptor–Ligand Complex

We have developed a unique in vivo system to determine the relationship between endogenous altered peptide ligands and the development of major histocompatibility complex class II– restricted T cells. Our studies use the 3.L2 T cell receptor (TCR) transgenic mouse, in which T cells are specific for...

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Detalles Bibliográficos
Autores principales: Williams, Calvin B., Engle, Deborah L., Kersh, Gilbert J., Michael White, J., Allen, Paul M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193645/
https://www.ncbi.nlm.nih.gov/pubmed/10330432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193645/
https://www.ncbi.nlm.nih.gov/pubmed/10330432

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