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Presentation of the Same Glycolipid by Different CD1 Molecules

Five CD1 molecules are expressed in humans and it is unclear whether they have specialized or redundant functions. We found that sulfatide is a promiscuous CD1-binding ligand and have isolated T cell clones that are specific for sulfatide and restricted by distinct CD1 molecules. These clones have b...

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Detalles Bibliográficos
Autores principales: Shamshiev, A., Gober, H.-J., Donda, A., Mazorra, Z., Mori, L., De Libero, G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193693/
https://www.ncbi.nlm.nih.gov/pubmed/11956292
http://dx.doi.org/10.1084/jem.20011963