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Ligand Binding Sites of Inducible Costimulator and High Avidity Mutants with Improved Function
Interaction between inducible costimulator (ICOS) and its ligand is implicated in the induction of cell-mediated and humoral immune responses. However, the molecular details of this interaction are unknown. We report here a mutagenesis analysis of residues in ICOS that are critical for ligand bindin...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193694/ https://www.ncbi.nlm.nih.gov/pubmed/11956294 http://dx.doi.org/10.1084/jem.20011607 |