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Link between Organ-specific Antigen Processing by 20S Proteasomes and CD8(+) T Cell–mediated Autoimmunity
Adoptive transfer of cross-reactive HSP60-specific CD8(+) T cells into immunodeficient mice causes autoimmune intestinal pathology restricted to the small intestine. We wondered whether local immunopathology induced by CD8(+) T cells can be explained by tissue-specific differences in proteasome-medi...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193696/ https://www.ncbi.nlm.nih.gov/pubmed/11956289 http://dx.doi.org/10.1084/jem.20011199 |