Link between Organ-specific Antigen Processing by 20S Proteasomes and CD8(+) T Cell–mediated Autoimmunity

Adoptive transfer of cross-reactive HSP60-specific CD8(+) T cells into immunodeficient mice causes autoimmune intestinal pathology restricted to the small intestine. We wondered whether local immunopathology induced by CD8(+) T cells can be explained by tissue-specific differences in proteasome-medi...

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Detalles Bibliográficos
Autores principales: Kuckelkorn, Ulrike, Ruppert, Thomas, Strehl, Britta, Jungblut, Peter R., Zimny-Arndt, Ursula, Lamer, Stephanie, Prinz, Immo, Drung, Ilse, Kloetzel, Peter-M., Kaufmann, Stefan H.E., Steinhoff, Ulrich
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193696/
https://www.ncbi.nlm.nih.gov/pubmed/11956289
http://dx.doi.org/10.1084/jem.20011199

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