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Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB(−/−) Mice

FcγRIIB is a potent lupus susceptibility gene as demonstrated by the observation that mice deficient in this molecule develop spontaneous antinuclear antibodies (ANA) and fatal glomerulonephritis when on the C57BL/6 background. To determine the mechanisms underlying the epistasis displayed by this g...

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Detalles Bibliográficos
Autores principales: Bolland, Silvia, Yim, Young-Sun, Tus, Katalin, Wakeland, Edward K., Ravetch, Jeffrey V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193704/
https://www.ncbi.nlm.nih.gov/pubmed/11994421
http://dx.doi.org/10.1084/jem.20020165