Cargando…

Genetic Modifiers of Systemic Lupus Erythematosus in FcγRIIB(−/−) Mice

FcγRIIB is a potent lupus susceptibility gene as demonstrated by the observation that mice deficient in this molecule develop spontaneous antinuclear antibodies (ANA) and fatal glomerulonephritis when on the C57BL/6 background. To determine the mechanisms underlying the epistasis displayed by this g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bolland, Silvia, Yim, Young-Sun, Tus, Katalin, Wakeland, Edward K., Ravetch, Jeffrey V.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193704/ https://www.ncbi.nlm.nih.gov/pubmed/11994421 http://dx.doi.org/10.1084/jem.20020165

Ejemplares similares

Lupus-like Disease in FcγRIIB(−/−) Mice Induces Osteopenia
por: Visitchanakun, Peerapat, et al.
Publicado: (2019)

A general requirement for FcγRIIB co-engagement of agonistic anti-TNFR antibodies
por: Li, Fubin, et al.
Publicado: (2012)

Impacts of FcγRIIB and FcγRIIIA gene polymorphisms on systemic lupus erythematous disease activity index
por: Karimifar, Mansoor, et al.
Publicado: (2021)

Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B cell activation to ameliorate systemic lupus erythematosus
por: Sheng, Linlin, et al.
Publicado: (2020)

Correction to: Impacts of FcγRIIB and FcγRIIIA gene polymorphisms on systemic lupus erythematous disease activity index
por: Karimifar, Mansoor, et al.
Publicado: (2022)

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program
por: Dhodapkar, Kavita M., et al.
Publicado: (2007)

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program
por: Dhodapkar, Kavita M., et al.
Publicado: (2007)

Regulation of Monoclonal Antibody Immunotherapy by FcγRIIB
por: Stopforth, Richard J., et al.
Publicado: (2016)

The Complex Association of FcγRIIb With Autoimmune Susceptibility
por: Verbeek, J. Sjef, et al.
Publicado: (2019)

Identification of candidate regulators of mandibular bone loss in FcγRIIB(-/-) Mice
por: Sakunrangsit, Nithidol, et al.
Publicado: (2021)

Helicobacter pylori Infection Increased Anti-dsDNA and Enhanced Lupus Severity in Symptomatic FcγRIIb-Deficient Lupus Mice
por: Surawut, Saowapha, et al.
Publicado: (2018)

Transmembrane domain dependent inhibitory function of FcγRIIB
por: Wang, Junyi, et al.
Publicado: (2018)

FcγRIIB is a T cell checkpoint in antitumor immunity
por: Farley, Clara R., et al.
Publicado: (2021)

Role of lipid nanodomains for inhibitory FcγRIIb function
por: Spiegel, Franziska, et al.
Publicado: (2023)

Etanercept prevents TNF-α mediated mandibular bone loss in FcγRIIb(-/-) lupus model
por: Sakunrangsit, Nithidol, et al.
Publicado: (2021)

Distinct cell-specific control of autoimmunity and infection by FcγRIIb
por: Brownlie, Rebecca J., et al.
Publicado: (2008)

High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis
por: Magnusson, Sofia E, et al.
Publicado: (2007)

IgG-Independent Co-aggregation of FcεRI and FcγRIIB Results in LYN- and SHIP1-Dependent Tyrosine Phosphorylation of FcγRIIB in Murine Bone Marrow-Derived Mast Cells
por: Gast, Mathias, et al.
Publicado: (2018)

Functional Role of FcγRIIB in the Regulation of Mesenchymal Stem Cell Function
por: Zhu, Tianyi, et al.
Publicado: (2016)

Targeting the Antibody Checkpoints to Enhance Cancer Immunotherapy–Focus on FcγRIIB
por: Teige, Ingrid, et al.
Publicado: (2019)

Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIa(R131) and FcγRIIa(H131)
por: Mimoto, F., et al.
Publicado: (2013)

Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232
por: Xu, Liling, et al.
Publicado: (2016)

Upregulation of FcγRIIB by resveratrol via NF-κB activation reduces B-cell numbers and ameliorates lupus
por: Jhou, Jyun-Pei, et al.
Publicado: (2017)

Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor
por: Georgescu, Maria T., et al.
Publicado: (2020)

B Lymphocyte Memory: Role of Stromal Cell Complement and FcγRIIB Receptors
por: Barrington, Robert A., et al.
Publicado: (2002)

FcγRIIb Balances Efficient Pathogen Clearance and the Cytokine-mediated Consequences of Sepsis
por: Clatworthy, Menna R., et al.
Publicado: (2004)

Dexamethasone Induces FcγRIIb Expression in RBL-2H3 Cells
por: Silwal, Prashanta, et al.
Publicado: (2012)

FcγRIIB-I232T polymorphic change allosterically suppresses ligand binding
por: Hu, Wei, et al.
Publicado: (2019)

FcγRIIb blockage: a promising immunotherapy target for severe COVID-19
por: He, Xuemei, et al.
Publicado: (2021)

Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is FcγRIIB Dependent
por: Hu, Xian-Zhen, et al.
Publicado: (2010)

Anti‐Inflammatory Immune Skewing Is Atheroprotective: Apoe(−/−)FcγRIIb(−/−) Mice Develop Fibrous Carotid Plaques
por: Harmon, Erin Y., et al.
Publicado: (2014)

Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling
por: Patin, Emmanuel C., et al.
Publicado: (2017)

The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease
por: Chang, Ling-Sai, et al.
Publicado: (2016)

FcγRIIb Inhibits Allergic Lung Inflammation in a Murine Model of Allergic Asthma
por: Dharajiya, Nilesh, et al.
Publicado: (2010)

FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape
por: Wu, Lei, et al.
Publicado: (2022)

FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation
por: Barlev, Ashley N., et al.
Publicado: (2022)

Antibody-Targeted TNFRSF Activation for Cancer Immunotherapy: The Role of FcγRIIB Cross-Linking
por: Liu, Luyan, et al.
Publicado: (2022)

FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms
por: Simpson, Alexander P., et al.
Publicado: (2022)

Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor FcγRIIB
por: Petkova, Stefka B., et al.
Publicado: (2006)

Development of self-reactive germinal center B cells and plasma cells in autoimmune FcγRIIB-deficient mice
por: Tiller, Thomas, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_i928i9ttkc30ngbn24dacr9kej