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The Activation-induced Deaminase Functions in a Postcleavage Step of the Somatic Hypermutation Process

Activation of B cells by antigen fuels two distinct molecular modifications of immunoglobulin (Ig) genes. Class-switch recombination (CSR) replaces the Igμ heavy chain constant region with a downstream constant region gene, thereby altering the effector function of the resulting antibodies. Somatic...

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Detalles Bibliográficos
Autores principales:	Papavasiliou, F. Nina, Schatz, David G.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193708/ https://www.ncbi.nlm.nih.gov/pubmed/11994424 http://dx.doi.org/10.1084/jem.20011858

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