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Identification of the In Vivo Role of a Viral bcl-2

Many γ-herpesviruses encode candidate oncogenes including homologues of host bcl-2 and cyclin proteins (v-bcl-2, v-cyclin), but the physiologic roles of these genes during infection are not known. We show for the first time in any virus system the physiologic role of v-bcl-2. A γ-herpesvirus v-bcl-2...

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Detalles Bibliográficos
Autores principales: Gangappa, Shivaprakash, van Dyk, Linda F., Jewett, Travis J., Speck, Samuel H., Virgin, Herbert W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193719/
https://www.ncbi.nlm.nih.gov/pubmed/11927636
http://dx.doi.org/10.1084/jem.20011825