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Role of p75 Neurotrophin Receptor in the Neurotoxicity by β-amyloid Peptides and Synergistic Effect of Inflammatory Cytokines

The neurodegenerative changes in Alzheimer's disease (AD) are elicited by the accumulation of β-amyloid peptides (Aβ), which damage neurons either directly by interacting with components of the cell surface to trigger cell death signaling or indirectly by activating astrocytes and microglia to...

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Detalles Bibliográficos
Autores principales: Perini, Giovanni, Della-Bianca, Vittorina, Politi, Valeria, Della Valle, Giuliano, Dal-Pra, Ilaria, Rossi, Filippo, Armato, Ubaldo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193732/
https://www.ncbi.nlm.nih.gov/pubmed/11927634
http://dx.doi.org/10.1084/jem.20011797