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Pharmacological Stimulation of the Cholinergic Antiinflammatory Pathway

Efferent activity in the vagus nerve can prevent endotoxin-induced shock by attenuating tumor necrosis factor (TNF) synthesis. Termed the “cholinergic antiinflammatory pathway,” inhibition of TNF synthesis is dependent on nicotinic α-bungarotoxin-sensitive acetylcholine receptors on macrophages. Vag...

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Detalles Bibliográficos
Autores principales: Bernik, Thomas R., Friedman, Steven G., Ochani, Mahendar, DiRaimo, Robert, Ulloa, Luis, Yang, Huan, Sudan, Samridhi, Czura, Christopher J., Ivanova, Svetlana M., Tracey, Kevin J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193742/
https://www.ncbi.nlm.nih.gov/pubmed/11901203
http://dx.doi.org/10.1084/jem.20011714