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Pharmacological Stimulation of the Cholinergic Antiinflammatory Pathway
Efferent activity in the vagus nerve can prevent endotoxin-induced shock by attenuating tumor necrosis factor (TNF) synthesis. Termed the “cholinergic antiinflammatory pathway,” inhibition of TNF synthesis is dependent on nicotinic α-bungarotoxin-sensitive acetylcholine receptors on macrophages. Vag...
Autores principales: | Bernik, Thomas R., Friedman, Steven G., Ochani, Mahendar, DiRaimo, Robert, Ulloa, Luis, Yang, Huan, Sudan, Samridhi, Czura, Christopher J., Ivanova, Svetlana M., Tracey, Kevin J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193742/ https://www.ncbi.nlm.nih.gov/pubmed/11901203 http://dx.doi.org/10.1084/jem.20011714 |
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