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Surface Cytotoxic T Lymphocyte–associated Antigen 4 Partitions Within Lipid Rafts and Relocates to the Immunological Synapse under Conditions of Inhibition of T Cell Activation

T cell activation through the T cell receptor (TCR) involves partitioning of receptors into discrete membrane compartments known as lipid rafts, and the formation of an immunological synapse (IS) between the T cell and antigen-presenting cell (APC). Compartmentalization of negative regulators of T c...

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Detalles Bibliográficos
Autores principales: Darlington, Peter J., Baroja, Miren L., Chau, Thu A., Siu, Eric, Ling, Vincent, Carreno, Beatriz M., Madrenas, Joaquín
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193751/
https://www.ncbi.nlm.nih.gov/pubmed/12021313
http://dx.doi.org/10.1084/jem.20011868