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Surface Cytotoxic T Lymphocyte–associated Antigen 4 Partitions Within Lipid Rafts and Relocates to the Immunological Synapse under Conditions of Inhibition of T Cell Activation
T cell activation through the T cell receptor (TCR) involves partitioning of receptors into discrete membrane compartments known as lipid rafts, and the formation of an immunological synapse (IS) between the T cell and antigen-presenting cell (APC). Compartmentalization of negative regulators of T c...
Autores principales: | Darlington, Peter J., Baroja, Miren L., Chau, Thu A., Siu, Eric, Ling, Vincent, Carreno, Beatriz M., Madrenas, Joaquín |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193751/ https://www.ncbi.nlm.nih.gov/pubmed/12021313 http://dx.doi.org/10.1084/jem.20011868 |
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