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Rapid Cytotoxic T Lymphocyte Activation Occurs in the Draining Lymph Nodes After Cutaneous Herpes Simplex Virus Infection as a Result of Early Antigen Presentation and Not the Presence of Virus

Localized cutaneous herpes simplex virus type 1 (HSV-1) infection leads to arming and initial expansion of cytotoxic T lymphocytes (CTLs) in the draining popliteal lymph nodes (PLNs) followed by migration and further proliferation in the spleen. To accurately characterize the sequence of events invo...

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Detalles Bibliográficos
Autores principales: Mueller, Scott N., Jones, Claerwen M., Smith, Chris M., Heath, William R., Carbone, Francis R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193766/
https://www.ncbi.nlm.nih.gov/pubmed/11877488
http://dx.doi.org/10.1084/jem.20012023