AID Mediates Hypermutation by Deaminating Single Stranded DNA

Activation-induced deaminase (AID) is a protein indispensable for the diversification of immunoglobulin (Ig) genes by somatic hypermutation (SHM), class switch recombination (CSR), and gene conversion. To date, the precise role of AID in these processes has not been determined. Here we demonstrate t...

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Detalles Bibliográficos
Autores principales: Dickerson, Sarah K., Market, Eleonora, Besmer, Eva, Papavasiliou, F. Nina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193777/
https://www.ncbi.nlm.nih.gov/pubmed/12756266
http://dx.doi.org/10.1084/jem.20030481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193777/
https://www.ncbi.nlm.nih.gov/pubmed/12756266
http://dx.doi.org/10.1084/jem.20030481

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