Steroid Hormone Synthesis by Vaccinia Virus Suppresses the Inflammatory Response to Infection

The 3β-hydroxysteroid dehydrogenase (3β-HSD) isoenzymes play a key role in cellular steroid hormone synthesis. Vaccinia virus (VV) also synthesizes steroid hormones with a 3β-HSD enzyme (v3β-HSD) encoded by gene A44L. Here we examined the effects of v3β-HSD in VV disease using wild-type (vA44L), del...

Descripción completa

Detalles Bibliográficos
Autores principales: Reading, Patrick C., Moore, Jeffrey B., Smith, Geoffrey L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193778/
https://www.ncbi.nlm.nih.gov/pubmed/12756265
http://dx.doi.org/10.1084/jem.20022201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193778/
https://www.ncbi.nlm.nih.gov/pubmed/12756265
http://dx.doi.org/10.1084/jem.20022201

Ejemplares similares