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Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2

Mismatch repair proteins participate in antibody class switch recombination, although their roles are unknown. Previous nucleotide sequence analyses of switch recombination junctions indicated that the roles of Msh2 and the MutL homologues, Mlh1 and Pms2, differ. We now asked if Msh2 and Mlh1 functi...

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Detalles Bibliográficos
Autores principales: Schrader, Carol E., Vardo, Joycelyn, Stavnezer, Janet
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193780/
https://www.ncbi.nlm.nih.gov/pubmed/12743174
http://dx.doi.org/10.1084/jem.20022190