Determinants of HIV-1 Mutational Escape From Cytotoxic T Lymphocytes

CD8(+) class I–restricted cytotoxic T lymphocytes (CTLs) usually incompletely suppress HIV-1 in vivo, and while analogous partial suppression induces antiretroviral drug-resistance mutations, epitope escape mutations are inconsistently observed. However, escape mutation depends on the net balance of...

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Detalles Bibliográficos
Autores principales: Yang, Otto O., Sarkis, Phuong Thi Nguyen, Ali, Ayub, Harlow, Jason D., Brander, Christian, Kalams, Spyros A., Walker, Bruce D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193781/
https://www.ncbi.nlm.nih.gov/pubmed/12743169
http://dx.doi.org/10.1084/jem.20022138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193781/
https://www.ncbi.nlm.nih.gov/pubmed/12743169
http://dx.doi.org/10.1084/jem.20022138

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