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Determinants of HIV-1 Mutational Escape From Cytotoxic T Lymphocytes

CD8(+) class I–restricted cytotoxic T lymphocytes (CTLs) usually incompletely suppress HIV-1 in vivo, and while analogous partial suppression induces antiretroviral drug-resistance mutations, epitope escape mutations are inconsistently observed. However, escape mutation depends on the net balance of...

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Detalles Bibliográficos
Autores principales:	Yang, Otto O., Sarkis, Phuong Thi Nguyen, Ali, Ayub, Harlow, Jason D., Brander, Christian, Kalams, Spyros A., Walker, Bruce D.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193781/ https://www.ncbi.nlm.nih.gov/pubmed/12743169 http://dx.doi.org/10.1084/jem.20022138

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