Enforced Granulocyte/Macrophage Colony-stimulating Factor Signals Do Not Support Lymphopoiesis, but Instruct Lymphoid to Myelomonocytic Lineage Conversion

We evaluated the effects of ectopic granulocyte/macrophage colony-stimulating factor (GM-CSF) signals on hematopoietic commitment and differentiation. Lineage-restricted progenitors purified from mice with the ubiquitous transgenic human GM-CSF receptor (hGM-CSFR) were used for the analysis. In cult...

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Detalles Bibliográficos
Autores principales: Iwasaki-Arai, Junko, Iwasaki, Hiromi, Miyamoto, Toshihiro, Watanabe, Sumiko, Akashi, Koichi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193786/
https://www.ncbi.nlm.nih.gov/pubmed/12756267
http://dx.doi.org/10.1084/jem.20021843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193786/
https://www.ncbi.nlm.nih.gov/pubmed/12756267
http://dx.doi.org/10.1084/jem.20021843

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