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Enforced Granulocyte/Macrophage Colony-stimulating Factor Signals Do Not Support Lymphopoiesis, but Instruct Lymphoid to Myelomonocytic Lineage Conversion
We evaluated the effects of ectopic granulocyte/macrophage colony-stimulating factor (GM-CSF) signals on hematopoietic commitment and differentiation. Lineage-restricted progenitors purified from mice with the ubiquitous transgenic human GM-CSF receptor (hGM-CSFR) were used for the analysis. In cult...
Autores principales: | Iwasaki-Arai, Junko, Iwasaki, Hiromi, Miyamoto, Toshihiro, Watanabe, Sumiko, Akashi, Koichi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193786/ https://www.ncbi.nlm.nih.gov/pubmed/12756267 http://dx.doi.org/10.1084/jem.20021843 |
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