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An Essential Role of Cytosolic Phospholipase A2α in Prostaglandin E2–mediated Bone Resorption Associated with Inflammation

Prostaglandin E (PGE)2 produced by osteoblasts acts as a potent stimulator of bone resorption. Inflammatory bone loss is accompanied by osteoclast formation induced by bone-resorbing cytokines, but the mechanism of PGE2 production and bone resorption in vivo is not fully understood. Using cytosolic...

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Detalles Bibliográficos
Autores principales: Miyaura, Chisato, Inada, Masaki, Matsumoto, Chiho, Ohshiba, Tomoyasu, Uozumi, Naonori, Shimizu, Takao, Ito, Akira
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193787/
https://www.ncbi.nlm.nih.gov/pubmed/12743173
http://dx.doi.org/10.1084/jem.20030015