Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

A number of diseases are due to lysosomal destabilization, which results in damaging cell loss. To investigate the mechanisms of lysosomal cell death, we characterized the cytotoxic action of two widely used quinolone antibiotics: ciprofloxacin (CPX) or norfloxacin (NFX). CPX or NFX plus UV light (N...

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Detalles Bibliográficos
Autores principales: Boya, Patricia, Andreau, Karine, Poncet, Delphine, Zamzami, Naoufal, Perfettini, Jean-Luc, Metivier, Didier, Ojcius, David M., Jäättelä, Marja, Kroemer, Guido
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193790/
https://www.ncbi.nlm.nih.gov/pubmed/12756268
http://dx.doi.org/10.1084/jem.20021952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193790/
https://www.ncbi.nlm.nih.gov/pubmed/12756268
http://dx.doi.org/10.1084/jem.20021952

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