Secondary Heavy Chain Rearrangement: A Mechanism for Generating Anti–double-stranded DNA B Cells

The chronic graft-versus-host (cGVH) reaction results in a syndrome that closely resembles systemic lupus erythematosus (SLE). It is induced in nonautoimmune mice by the transfer of alloreactive T cells. The availability of anti-DNA transgenes allows us to study the genetic origins of autoantibodies...

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Detalles Bibliográficos
Autores principales: Sekiguchi, Debora R., Eisenberg, Robert A., Weigert, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193805/
https://www.ncbi.nlm.nih.gov/pubmed/12515811
http://dx.doi.org/10.1084/jem.20020737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193805/
https://www.ncbi.nlm.nih.gov/pubmed/12515811
http://dx.doi.org/10.1084/jem.20020737

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