Prospective Estimation of Recombination Signal Efficiency and Identification of Functional Cryptic Signals in the Genome by Statistical Modeling

The recombination signals (RS) that guide V(D)J recombination are phylogenetically conserved but retain a surprising degree of sequence variability, especially in the nonamer and spacer. To characterize RS variability, we computed the position-wise information, a measure correlated with sequence con...

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Detalles Bibliográficos
Autores principales: Cowell, Lindsay G., Davila, Marco, Yang, Kaiyong, Kepler, Thomas B., Kelsoe, Garnett
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193808/
https://www.ncbi.nlm.nih.gov/pubmed/12538660
http://dx.doi.org/10.1084/jem.20020250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193808/
https://www.ncbi.nlm.nih.gov/pubmed/12538660
http://dx.doi.org/10.1084/jem.20020250

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