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Vaginal Submucosal Dendritic Cells, but Not Langerhans Cells, Induce Protective Th1 Responses to Herpes Simplex Virus-2

Herpes simplex virus (HSV) type 2 infection occurs primarily at the genital mucosal surfaces and is a leading cause of ulcerative lesions. Despite the availability of animal models for HSV-2 infection, little is known regarding the mechanism of immune induction within the vaginal mucosa. Here, we ex...

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Detalles Bibliográficos
Autores principales: Zhao, Xinyan, Deak, Eszter, Soderberg, Kelly, Linehan, Melissa, Spezzano, David, Zhu, Jia, Knipe, David M., Iwasaki, Akiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193810/
https://www.ncbi.nlm.nih.gov/pubmed/12538655
http://dx.doi.org/10.1084/jem.20021109