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Vaginal Submucosal Dendritic Cells, but Not Langerhans Cells, Induce Protective Th1 Responses to Herpes Simplex Virus-2
Herpes simplex virus (HSV) type 2 infection occurs primarily at the genital mucosal surfaces and is a leading cause of ulcerative lesions. Despite the availability of animal models for HSV-2 infection, little is known regarding the mechanism of immune induction within the vaginal mucosa. Here, we ex...
Autores principales: | Zhao, Xinyan, Deak, Eszter, Soderberg, Kelly, Linehan, Melissa, Spezzano, David, Zhu, Jia, Knipe, David M., Iwasaki, Akiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193810/ https://www.ncbi.nlm.nih.gov/pubmed/12538655 http://dx.doi.org/10.1084/jem.20021109 |
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