Cargando…

Differential Regulation of Cathepsin S and Cathepsin L in Interferon γ–treated Macrophages

Cathepsin S (catS) and cathepsin L (catL) mediate late stages of invariant chain (Ii) degradation in discrete antigen-presenting cell types. Macrophages (Mφs) are unique in that they express both proteases and here we sought to determine the relative contribution of each enzyme. We observe that catL...

Descripción completa

Detalles Bibliográficos
Autores principales: Beers, Courtney, Honey, Karen, Fink, Susan, Forbush, Katherine, Rudensky, Alexander
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193812/
https://www.ncbi.nlm.nih.gov/pubmed/12538657
http://dx.doi.org/10.1084/jem.20020978