Flt3 Ligand–treated Neonatal Mice Have Increased Innate Immunity Against Intracellular Pathogens and Efficiently Control Virus Infections

Flt-3 ligand (FL), a hematopoetic growth factor, increases the number of dendritic cells (DCs), B cells, and natural killer cells in adult mice but the effect in neonates was unknown. We show that FL treatment of newborn mice induced a >100-fold increase in the innate resistance against infection...

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Detalles Bibliográficos
Autores principales: Vollstedt, Sabine, Franchini, Marco, Hefti, Hans P., Odermatt, Bernhard, O'Keeffe, Meredith, Alber, Gottfried, Glanzmann, Bettina, Riesen, Matthias, Ackermann, Mathias, Suter, Mark
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193820/
https://www.ncbi.nlm.nih.gov/pubmed/12615899
http://dx.doi.org/10.1084/jem.20021900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193820/
https://www.ncbi.nlm.nih.gov/pubmed/12615899
http://dx.doi.org/10.1084/jem.20021900

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