T Cell Receptor Gene Rearrangement Lineage Analysis Reveals Clues for the Origin of Highly Restricted Antigen-specific Repertoires

Due to ordered, stage-specific T cell receptor (TCR)-β and -α locus gene rearrangements and cell division during T cell development, a given, ancestral TCR-β locus VDJ rearrangement might be selected into the mature T cell repertoire as a small cohort of “half-sibling” progeny expressing identical T...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamrouni, Abdelbasset, Aublin, Anne, Guillaume, Philippe, Maryanski, Janet L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193826/
https://www.ncbi.nlm.nih.gov/pubmed/12615901
http://dx.doi.org/10.1084/jem.20021945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193826/
https://www.ncbi.nlm.nih.gov/pubmed/12615901
http://dx.doi.org/10.1084/jem.20021945

Ejemplares similares