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T Cell Receptor Gene Rearrangement Lineage Analysis Reveals Clues for the Origin of Highly Restricted Antigen-specific Repertoires

Due to ordered, stage-specific T cell receptor (TCR)-β and -α locus gene rearrangements and cell division during T cell development, a given, ancestral TCR-β locus VDJ rearrangement might be selected into the mature T cell repertoire as a small cohort of “half-sibling” progeny expressing identical T...

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Detalles Bibliográficos
Autores principales:	Hamrouni, Abdelbasset, Aublin, Anne, Guillaume, Philippe, Maryanski, Janet L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193826/ https://www.ncbi.nlm.nih.gov/pubmed/12615901 http://dx.doi.org/10.1084/jem.20021945

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