Restricting Zap70 Expression to CD4(+)CD8(+) Thymocytes Reveals a T Cell Receptor–dependent Proofreading Mechanism Controlling the Completion of Positive Selection

Although T cell receptor (TCR) signals are essential for intrathymic T cell–positive selection, it remains controversial whether they only serve to initiate this process, or whether they are required throughout to promote thymocyte differentiation and survival. To address this issue, we have devised...

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Detalles Bibliográficos
Autores principales: Liu, Xiaolong, Adams, Anthony, Wildt, Kathryn F., Aronow, Bruce, Feigenbaum, Lionel, Bosselut, Rémy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193832/
https://www.ncbi.nlm.nih.gov/pubmed/12566420
http://dx.doi.org/10.1084/jem.20021698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193832/
https://www.ncbi.nlm.nih.gov/pubmed/12566420
http://dx.doi.org/10.1084/jem.20021698

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