Transgenic Expression of the Activating Natural Killer Receptor Ly49H Confers Resistance to Cytomegalovirus in Genetically Susceptible Mice

Natural resistance to infection with mouse cytomegalovirus (MCMV) is controlled by a dominant locus, Cmv1. Cmv1 is linked to the Ly49 family of natural killer receptors on distal chromosome 6. While some studies localized Cmv1 as distal to the Ly49 gene cluster, genetic and functional analysis ident...

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Detalles Bibliográficos
Autores principales: Lee, Seung-Hwan, Zafer, Ahmed, de Repentigny, Yves, Kothary, Rashmi, Tremblay, Michel L., Gros, Philippe, Duplay, Pascale, Webb, John R., Vidal, Silvia M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193863/
https://www.ncbi.nlm.nih.gov/pubmed/12591908
http://dx.doi.org/10.1084/jem.20021713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193863/
https://www.ncbi.nlm.nih.gov/pubmed/12591908
http://dx.doi.org/10.1084/jem.20021713

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