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Complementary Role of CD4(+) T Cells and Secondary Lymphoid Tissues for Cross-presentation of Tumor Antigen to CD8(+) T Cells

MHC class I–restricted tumor antigens can be presented to CD8(+) T cells by two distinct pathways: via direct and indirect presentation. The relative contribution of these two pathways toward the initial activation of tumor antigen–specific CD8(+) T cells and their subsequent tumor rejection is stil...

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Detalles Bibliográficos
Autores principales: Yu, Ping, Spiotto, Michael T., Lee, Youjin, Schreiber, Hans, Fu, Yang-Xin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193872/
https://www.ncbi.nlm.nih.gov/pubmed/12695490
http://dx.doi.org/10.1084/jem.20021804