Human Immunoglobulin M Memory B Cells Controlling Streptococcus pneumoniae Infections Are Generated in the Spleen

Splenectomized and asplenic patients have a high incidence of infections by encapsulated bacteria and do not respond to polysaccharide vaccines. To understand whether the absence of the spleen is associated with a defined B cell defect, we analyzed B cell subsets in the peripheral blood. We found th...

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Detalles Bibliográficos
Autores principales: Kruetzmann, Stephanie, Rosado, M. Manuela, Weber, Holger, Germing, Ulrich, Tournilhac, Olivier, Peter, Hans-Hartmut, Berner, Reinhard, Peters, Anke, Boehm, Thomas, Plebani, Alessandro, Quinti, Isabella, Carsetti, Rita
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193885/
https://www.ncbi.nlm.nih.gov/pubmed/12682112
http://dx.doi.org/10.1084/jem.20022020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193885/
https://www.ncbi.nlm.nih.gov/pubmed/12682112
http://dx.doi.org/10.1084/jem.20022020

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