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Combined Deficiency of p50 and cRel in CD4(+) T Cells Reveals an Essential Requirement for Nuclear Factor κB in Regulating Mature T Cell Survival and In Vivo Function
Signaling pathways involved in regulating T cell proliferation and survival are not well understood. Here we have investigated a possible role of the nuclear factor (NF)-κB pathway in regulating mature T cell function by using CD4(+) T cells from p50(−/−) cRel(−/−) mice, which exhibit virtually no i...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193891/ https://www.ncbi.nlm.nih.gov/pubmed/12668645 http://dx.doi.org/10.1084/jem.20021610 |