Cargando…

CD1d-expressing Dendritic Cells but Not Thymic Epithelial Cells Can Mediate Negative Selection of NKT Cells

Natural killer T (NKT) cells are a unique immunoregulatory T cell population that is positively selected by CD1d-expressing thymocytes. Previous studies have shown that NKT cells exhibit autoreactivity, which raises the question of whether they are subject to negative selection. Here, we report that...

Descripción completa

Detalles Bibliográficos
Autores principales: Chun, Taehoon, Page, Michael J., Gapin, Laurent, Matsuda, Jennifer L., Xu, Honglin, Nguyen, Hanh, Kang, Hyung-Sik, Stanic, Aleksandar K., Joyce, Sebastian, Koltun, Walter A., Chorney, Michael J., Kronenberg, Mitchell, Wang, Chyung-Ru
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193895/
https://www.ncbi.nlm.nih.gov/pubmed/12682110
http://dx.doi.org/10.1084/jem.20021366